The maxillary lateral incisor agenesis (MLIA) brings orthodontic and prosthetic problems of lifelong maintenance, family counseling, complex treatment plans and an interdisciplinary approach. The MLIA can be treated by closing or opening spaces, and the cases are finished with composite resin additions (RC) or dental implants or resin bonded bridgework (RBB), respectively, after orthodontics, based on biological parameters. Both options require time-stable adhesive joints coupled with materials of adequate mechanical performance. We can minimize errors, reduce faulty predictions, and improve results with virtual prototyping using finite element analysis (FE), based on computed tomography (CT). FE analysis of pressure / strain on dental structure and biomaterials, varying tooth preparation designs and types of resin or ceramic reconstruction, can be made. It is intended to analyze in vitro and monitor the Bisphenol-A in CR and PAR to be used in the finalization of MLIA cases in young patients and to create an efficient virtual model to compare different joints, designs and materials.