Oral Diseases

Team leader

Major interests

The mission of this research line is to develop and apply research to understand, prevent, diagnose, and treat diseases affecting the orofacial region.
The specific objectives are:
i) To characterize the periodontal disease
Research activities include: antimicrobial potential of the Leukocyte-Platelet Rich Fibrin (L-PRF) in dentistry; association of periodontitis with systemic diseases; 16S rDNA metagenomic analysis for an oral infectious-inflammatory scale; new markers of peri-implant diseases and periodontitis; laser as an adjunct treatment in Peri-implantitis and periodontitis.
ii) To characterize the relationship between temporomandibular disorders with headaches
Research activities include: genome-wide approach to assess association between the two disorders; Physiotherapy in pain reduction and function improvement.
iii) To study congenitally missing teeth
Research activities include: miRNA profiling in patients with maxillary lateral incisor agenesis; minimally invasive rehabilitation of missing tooth.
iv) To improve attachments used with implant supported denture
Research activities include: new attachment to improve durability, reliability and retention capacity of implant supported denture.
v) To promote public oral health knowledge and good practices
 Activities include: organization of promotion activities at the north of Portugal; public awareness and knowledge of dental/oral practices and diseases (hygiene, cancer, periodontitis, caries), namely among school children. 

Current Projects


Publications Highlights

Monteiro L, Delgado ML, Garcês F, Machado M, Ferreira F, Martins M, Salazar F, Pacheco JJ. (2019). A histological evaluation of the surgical margins from human oral fibrous-epithelial lesions excised with CO2 laser, Diode laser, Er:YAG laser, Nd:YAG laser, electrosurgical scalpel and cold scalpel. Med Oral Patol Oral Cir Bucal. 2019 Mar 1;24(2):e271-e280. doi: 10.4317/medoral.22819.

Zacca, Rodrigo; Azevedo, Rui; Ramos, Valdir R. Jr; Abraldes, José A.; Vilas-Boas, João P.; Castro, Flávio Antônio de Souza; Pyne, David B.; Fernandes, Ricardo J. (2019). Biophysical Follow-up of Age-Group Swimmers During a Traditional Three-Peak Preparation Program. The Journal of Strength & Conditioning Research XX(X) (10.1519/JSC.0000000000002964)

Bucchi C, del Fabbro M, Arias A, Fuentes R, Mendes JM, Ordonneau M, Orti V, Manzanares-Céspedes MC (2019). Multicenter study of patients’ preferences and concerns regarding the origin of bone grafts utilized in dentistry. Patient Preference and Adherence. 2019 (13), 179-185.

Zacca, R.; Azevedo, R.; Figueiredo, P.; Vilas-Boas, J.P.; Castro, F.A.S.; Pyne, D.B.; Fernandes, R.J. (2019). VO2FITTING: A Free and Open-Source Software for Modelling Oxygen Uptake Kinetics in Swimming and other Exercise Modalities. Sports 2019, 7, 31.

Zacca, R., Toubekis, A., Freitas, L., Silva, A.F., Azevedo, R., Vilas-Boas, J.P., Pyne, D.B., Castro, F. A.de S. & Fernandes, R.J. (2019). Effects of detraining in age-group swimmers performance, energetics and kinematics, Journal of Sports Sciences, DOI: 10.1080/02640414.2019.1572434

Gomes AF, Pinho T. (2019). Esthetic perception of asymmetric canines treated with space closure in maxillary lateral incisor agenesis. Int J Esthet Dent. 2019;14(1):30-38. PMID: 30714052.

Manuel Mendes, J., Souza, L., Neves, L., Aroso, C., & Sérgio Silva, A. (2019). Study of Complications Associated with Placement of Overdentures on Implants. CPQ Dentistry, 1(4), 01-20.

Jonsson L., Magnusson TE., Thordarson A 2 , Jonsson T., Geller F 3 , Feenstra B., Melbye M., Nohr EA., Vucic S., Dhamo B., Rivadeneira F., Ongkosuwito EM., Wolvius EB., Leslie EJ., Marazita ML., Howe BJ., Moreno Uribe LM., Alonso I., Santos M., Pinho T., Jonsson R. , Audolfsson G. , Gudmundsson L., Nawaz MS., Olafsson S., Gustafsson O., Ingason A., Unnsteinsdottir U., Bjornsdottir G., Walters GB., Zervas M., Oddsson A., Gudbjartsson DF., Steinberg S., Stefansson H., & Stefansson K. (2018). Rare and Common Variants Conferring Risk of Tooth Agenesis. Journal of Dental Research. Jan 1:22034517750109.

Zacca R; Azevedo R.; Chainok P.; Vilas-Boas J.P.; Castro F.A. de S. ; Pyne D.B. ; Fernandes R.J. (2018). Monitoring Age-Group Swimmers Over a Training Macrocycle: Energetics, Technique, and Anthropometrics. Journal of Strength and Conditioning Research. Publish Ahead of Print():, AUG 2018

Gomes AF, Pinho T. (2018). Esthetic perception of asymmetric canines treated with space closure in maxillary lateral incisor agenesis. International Journal Esthetic Dentistry (in press).

Lamas C, Lavall A, Pinho T. (2018). Position and eruption of permanent maxillary canine in cases of maxillary lateral incisor agenesis in mixed dentition. Journal of Clinical Pediatric Dentistry. 42(3);240-246.

Ribas J, Paço M; Pinho T. (2018). Perception of facial aesthetics by different observers panels in Class II with mandibular retrusion. International Journal Esthetic Dentistry 13(2):208-219.

Silva, A.S., Sá, J. de, Aroso, C.M., Santos, E, Neves, L., and Mendes, J.M. (2018). Rehabilitation of an atrophic jaw with three short implants and a customized milled bar overdenture. Australian Medical Journal 2018;11(12):565–572

Machado, S. C., Manzanares-Céspedes, M. C., Ferreira-Moreira, J., Ferreira-Pacheco, J. J., Rompante, P. A., & Ustrell-Torrent, J. M. (2018). A sample of non-nutritive sucking habits (pacifier and digit) in portuguese children and its relation with the molar classes of angle. Journal of clinical and experimental dentistry, 10(12), e1161-e1166. doi:10.4317/jced.55284

Aroso C., Silva AS., Ustrell R., Mendes JM., Braga AC., Berastegui E., & Escuin T (2016). Effect of abutment angulation in the retention and durability of three overdenture attachment systems: An in vitro study. J Adv Prosthodont. 8(1):21-29.

Relvas M., Tomás I., Casares-De-Cal Mde L., & Velazco C. (2015). Evaluation of a new oral health scale of infectious potential based on the salivary microbiota. Clinical Oral Investigation. Apr 19(3), 717-28.

Alves-Ferreira M., Pinho T., Sousa A., Sequeiros J., Lemos C., & Alonso I. (2014). Identification of genetic risk factors for maxillary lateral incisor agenesis. Journal of Dental Research, 93 (5), pp. 452-458.

Mesquita B., Gonçalves M.J., Pacheco P., Lopes J., Salazar F., Relvas M., Coelho, C., Pacheco J.J., & Velazco, C. (2014). Helicobacter pylori identification: A diagnostic/confirmatory method for evaluation. Current Microbiology, 69 (3), pp. 245-251.


Oral Diseases Team

PhD Members

PhD Students

MSc Students